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Retinal Degenerative Diseases Bibliography

by DB-LINK on May 1, 2009
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This is a partial list of materials on this topic available from the NCDB Catalog Database.  If you have additional questions, please contact us via email: info@nationaldb.org

Updated 6/2009


1994-0514

Answers To Your Questions About Retinitis Pigmentosa: & Other Retinal Degenerative Diseases --RP Foundation Fighting Blindness. Baltimre, MD: RP Foundation Fighting Blindness. (1986) Using a question and answer format, booklet offers basic information about the causes and impact of retinitis pigmentosa (RP).

2005-0038

Clinical Trial of Docosahexaenoic Acid in Patients with Retinitis Pigmentosa Receiving Vitamin A Treatment --Berson, Eliot, MD; Rosner, Bernard, PhD; Sandberg, Michael, PhD. American Medical Association. Archives of Opthamology, Vol 122, September 2004, p.1297-1305. (2004) To determine whether docosahexaenoic acid (DHA) slows the course of retinal degeneration in patients with retinitis pigmentosa who are receiving vitamin A. No significant differences in decline in ocular function were found between the DHA + A group and control + A group over a 4 year interval.

2002-0087

Foundation Researchers Restore Vision in Canine Model of Childhood Blindness --Hoglund, Tom. A NEWSLETTERS FOR FRIENDS OF THE FOUNDATION FIGHTING BLINDNESS, Summer 2001, pp.1-3. (2001) This article describes research in retinal degeneration in which scientists used gene therapy to restore vision in a canine model of severe childhood blindness, known clinically as Leber congenital amaurosis (LCA). The finding represents the first time researchers successfully restored vision in a large animal model of retinal degeneration.

2005-0037

Further Evaluation of Docosahexaenoic Acid in Patients with Retinitis Pigmentosa Receiving Vitamin A Treatment --Berson, Eliot, MD; Rosner, Bernard, PhD; Sandberg, Michael, PhD. American Medical Association. Archives of Opthamology, Vol 122, September 2004, p.1306-1314. (2004) To determine whether docosahexaenoic acid (DHA) slows the course of retinal degeneration in patients with retinitis pigmentosa who are receiving vitamin A, 208 patients were randomly assigned DHA + Vitamin A or fatty acid + Vitamin A (control + A). Among patients not take A prior to the study, those in the DHA + A group had a slower decline in field sensitivity and electroretinogram amplitude than those in control +A over the first two years. These results were not observed in years 3 and 4 of the follow up or among patients taking vitamin A prior to entry into the study.

2005-0060

Genetics in RP and Retinal Degenerative Diseases: Discoveries, Breakthroughs, and Challenges --Shaberman, Ben. Maryland: Foundation Fighting Blindness. (2005) Discusses the current breakthroughs and therapies in genetic work related to retinal degenerative diseases including genetic breakthroughs in Usher syndrome and Stargardt Disease.

2003-0231

Inheritance of Retinal Degenerations: Information on Basic Genetics and Genetic Testing Hunt Valley, MD: Foundation Fighting Blindness. (2000) This booklet is a reprint of the same document published in 1995. It is intended for persons who have a retinal degenerative disease or members of their family. It can be used to prepare for a genetic counseling session and it may be referred to after counseling to help the reader remember what was discussed.

2004-0530

Progress in Treating Retinal Degenerations --Richman, Elaine A., Ph.D. The Foundation Fighting Blindness Newsletter. IN FOCUS, Spring 2004, pp. 1, 9-15. (2004) This article provides information on a variety of new treatments for retinal degeneration. It includes descriptions of various presentations at the Foundation Fighting Blindness Scientific Advisory Board meeting in 2004. Presentation topics include: finding the genes, genotyping, gene therapy for RD, Leber's Disease, and other forms of RP, cell biology, new pharmaceutical therapies, nutritional approaches, transplant, and electronic implants.

1997-0147

Retinal Hemodynamics in Retinitis Pigmentosa --Grunwald, Juan E., M.D.; Maguire, Albert M., M.D.; Dupont, Joan. AMERICAN JOURNAL OF OPHTHALMOLOGY, vol. 122, #4, October 1996, pp.502-508. (1996) This study of eight individuals with RP, or retinitis pigmentosa, indicates that retinal blood flow is significantly reduced in patients with RP, possibly as a result of vascular remodeling in response to reduced metabolic demand. Further studies are needed in order to determine how early in the disease process these changes occur and how they correlate with severity of disease, extent of photoreceptor degeneration, or both. Measurements of retinal hemodynamics may be of use in monitoring the progression of the disease and the effects of therapy.


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